Fabrication and Characterization of Tedizolid Phosphate Nanocrystals for Topical Ocular Application: Improved Solubilization and In Vitro Drug Release

Fabrication and Characterization of Tedizolid Phosphate Nanocrystals for Topical Ocular Application: Improved Solubilization and In Vitro Drug Release

Positively charged NCs of TZP (0.1%, <i>w</i>/<i>v</i>) for ocular use were prepared by the antisolvent precipitation method. TZP is a novel 5-Hydroxymethyl-Oxazolidinone class of antibiotic and is effective against many drug-resistant bacterial infections. Even the phosphate...

Full description

Bibliographic Details
Main Authors: Mohd Abul Kalam, Muzaffar Iqbal, Abdullah Alshememry, Musaed Alkholief, Aws Alshamsan
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
tedizolid phosphate
nanocrystals
thermal characterization
in vitro release
stability
Online Access:https://www.mdpi.com/1999-4923/14/7/1328

Internet

https://www.mdpi.com/1999-4923/14/7/1328

Similar Items