Single-cell RNA sequencing analysis reveals the heterogeneity of IL-10 producing regulatory B cells in lupus-prone mice

Single-cell RNA sequencing analysis reveals the heterogeneity of IL-10 producing regulatory B cells in lupus-prone mice

IntroductionB cells can have both pathogenic and protective roles in autoimmune diseases, including systemic lupus erythematosus (SLE). Deficiencies in the number or immunosuppressive function of IL-10 producing regulatory B cells (Bregs) can cause exacerbated autoimmune inflammation. However, the e...

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Bibliographic Details
Main Authors: Andrea R. Daamen, Razan M. Alajoleen, Amrie C. Grammer, Xin M. Luo, Peter E. Lipsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
lupus
Breg
single-cell
transcriptomics
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1282770/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1282770/full

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