Long-term effects of early antiretroviral initiation on HIV reservoir markers: a longitudinal analysis of the MERLIN clinical study

Summary: Background: Early antiretroviral therapy (ART) initiation (ie, within 3 months of infection) limits establishment of the HIV reservoir. However, the effect of early ART initiation on the long-term dynamics of the pool of infected cells remains unclear. Methods: In this longitudinal analysi...

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Bibliographic Details
Main Authors: Marta Massanella, PhD, Rachel A Bender Ignacio, MD, Javier R Lama, MD, Amélie Pagliuzza, MSc, Sayan Dasgupta, PhD, Ricardo Alfaro, MS, Jessica Rios, MS, Carmela Ganoza, MD, Delia Pinto-Santini, PhD, Trupti Gilada, MD, Ann Duerr, ProfMD, Nicolas Chomont, PhD
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:The Lancet Microbe
Online Access:http://www.sciencedirect.com/science/article/pii/S2666524721000100