Lipopolysaccharide alters CEBPβ signaling and reduces estradiol production in bovine granulosa cells

Abstract Background Bacterial infection of the uterus in postpartum dairy cows limits ovarian follicle growth, reduces blood estradiol concentrations, and leads to accumulation of bacterial lipopolysaccharide (LPS) in ovarian follicular fluid. Although treating granulosa cells with LPS in vitro decr...

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Bibliographic Details
Main Authors: Mackenzie J. Dickson, I. Martin Sheldon, John J. Bromfield
Format: Article
Language:English
Published: BMC 2022-10-01
Series:CABI Agriculture and Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s43170-022-00133-3