Single Cell Determination of 7,8-dihydro-8-oxo-2′-deoxyguanosine by Fluorescence Techniques: Antibody vs. Avidin Labeling

Single Cell Determination of 7,8-dihydro-8-oxo-2′-deoxyguanosine by Fluorescence Techniques: Antibody vs. Avidin Labeling

An important biomarker of oxidative damage in cellular DNA is the formation of 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-oxodG). Although several methods are available for the biochemical analysis of this molecule, its determination at the single cell level may provide significant advantages when inves...

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Bibliographic Details
Main Authors: Giusy Maraventano, Giulio Ticli, Ornella Cazzalini, Lucia A. Stivala, Mariella Ramos-Gonzalez, José-Luis Rodríguez, Ennio Prosperi
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
7,8-dihydro-8-oxo-2′-deoxyguanosine
oxidative DNA damage
immunofluorescence
avidin binding
Online Access:https://www.mdpi.com/1420-3049/28/11/4326

Internet

https://www.mdpi.com/1420-3049/28/11/4326

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