Glial cells react to closed head injury in a distinct and spatiotemporally orchestrated manner

Abstract Traumatic brain injury (TBI) is a leading cause of mortality and disability worldwide. Acute neuroinflammation is a prominent reaction after TBI and is mostly initiated by brain-resident glial cells such as microglia, NG2-glia and astrocytes. The magnitude of this reaction paves the way for...

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Bibliographic Details
Main Authors: Ester Nespoli, Marsela Hakani, Tabea Melissa Hein, Stephanie Nadine May, Karin Danzer, Thomas Wirth, Bernd Baumann, Leda Dimou
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52337-4