Abelmoschus esculentus subfractions attenuate Aβ and tau by regulating DPP-4 and insulin resistance signals
Abstract Background Insulin resistance could be associated with the development of Alzheimer disease (AD). The neuropathological hallmarks of AD are beta amyloid (Aβ) produced from sequential cleavage initiated by β-secretase and degraded by insulin degradation enzyme (IDE), as well as hyperphosphor...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | BMC Complementary Medicine and Therapies |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12906-020-03163-4 |