M2 macrophage-derived exosomal microRNAs inhibit cell migration and invasion in gliomas through PI3K/AKT/mTOR signaling pathway

M2 macrophage-derived exosomal microRNAs inhibit cell migration and invasion in gliomas through PI3K/AKT/mTOR signaling pathway

Abstract Background Glioma, the most common primary brain tumor, account Preparing figures for 30 to 40% of all intracranial tumors. Herein, we aimed to study the effects of M2 macrophage-derived exosomal microRNAs (miRNAs) on glioma cells. Methods First, we identified seven differentially expressed...

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Bibliographic Details
Main Authors: Jie Yao, Zefen Wang, Yong Cheng, Chao Ma, Yahua Zhong, Yilei Xiao, Xu Gao, Zhiqiang Li
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Translational Medicine
Subjects:
M2 macrophage
Exosome
hsa-miR-15a-5p
hsa-miR-92a-3p
Glioma
PI3K/AKT/mTOR
Online Access:https://doi.org/10.1186/s12967-021-02766-w

Internet

https://doi.org/10.1186/s12967-021-02766-w

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