Comparative gene co-expression network analysis of epithelial to mesenchymal transition reveals lung cancer progression stages

Comparative gene co-expression network analysis of epithelial to mesenchymal transition reveals lung cancer progression stages

Abstract Background The epithelial to mesenchymal transition (EMT) plays a key role in lung cancer progression and drug resistance. The dynamics and stability of gene expression patterns as cancer cells transition from E to M at a systems level and relevance to patient outcomes are unknown. Methods...

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Bibliographic Details
Main Authors: Daifeng Wang, John D. Haley, Patricia Thompson
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cancer
Subjects:
Lung cancer
Epithelial to mesenchymal transition
Gene regulatory network
Comparative network analysis
EMT-dynamic signature genes
Cancer progression
Online Access:http://link.springer.com/article/10.1186/s12885-017-3832-1

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http://link.springer.com/article/10.1186/s12885-017-3832-1

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