Restorative therapy using microglial depletion and repopulation for central nervous system injuries and diseases

Microglia are important resident immune cells in the central nervous system (CNS) and play an important role in its development, homeostasis, and disease treatments. Activated microglia perform diverse functions in mouse models of CNS neurodegenerative diseases or deficits. In humans, microglia have...

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Bibliographic Details
Main Authors: Weipeng Shi, Jing Zhang, Zhen Shang, Yingze Zhang, Yanzhi Xia, Haitao Fu, Tengbo Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.969127/full