Daidzin improves the cisplatin chemosensitivity for osteosarcoma via binding to β-catenin protein and suppressing the wnt pathway

Abstract Osteosarcoma (OS) mainly occurs in adolescents and children, accompanied with chemotherapy resistance as well as unsatisfactory treatment outcome. Recent studies have discovered a series of natural products with anticancer activity, which have important translational value. Daidzin has been...

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Bibliographic Details
Main Authors: Peng Wang, Hao Lu, Chi Zhang, Renwei Wang, Xiaobo Chen, Lixin Qiao, Zhiyong Wang, Wenge Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-89766-8