Overexpression of <i>TcNTPDase-1</i> Gene Increases Infectivity in Mice Infected with <i>Trypanosoma cruzi</i>

Overexpression of <i>TcNTPDase-1</i> Gene Increases Infectivity in Mice Infected with <i>Trypanosoma cruzi</i>

Ecto-nucleoside triphosphate diphosphohydrolases (NTPDases) are enzymes located on the surface of the <i>T. cruzi</i> plasma membrane, which hydrolyze a wide range of tri-/-diphosphate nucleosides. In this work, we used previously developed genetically modified strains of <i>Trypan...

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Bibliographic Details
Main Authors: Natália Lins da Silva-Gomes, Leonardo Alexandre de Souza Ruivo, Claudia Moreira, Marcelo Meuser-Batista, Cristiane França da Silva, Denise da Gama Jaen Batista, Stênio Fragoso, Gabriel Melo de Oliveira, Maria de Nazaré Correia Soeiro, Otacilio C. Moreira
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Trypanosoma cruzi</i>
chagas disease
ecto-NTPDases
TcNTPDase
virulence
Online Access:https://www.mdpi.com/1422-0067/23/23/14661

Internet

https://www.mdpi.com/1422-0067/23/23/14661

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