CCL5/CCR5-mediated peripheral inflammation exacerbates blood‒brain barrier disruption after intracerebral hemorrhage in mice

CCL5/CCR5-mediated peripheral inflammation exacerbates blood‒brain barrier disruption after intracerebral hemorrhage in mice

Abstract Background Owing to metabolic disequilibrium and immune suppression, intracerebral hemorrhage (ICH) patients are prone to infections; according to a recent global analysis of stroke cases, approximately 10 million new-onset ICH patients had experienced concurrent infection. However, the int...

Full description

Bibliographic Details
Main Authors: Jie Lin, Ya Xu, Peiwen Guo, Yù-Jié Chen, Jiru Zhou, Min Xia, Binbin Tan, Xin Liu, Hua Feng, Yujie Chen
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Translational Medicine
Subjects:
Intracerebral hemorrhage
Blood‒brain barrier
C–C chemokine receptor 5
Peripheral inflammation
Neuroinflammation
Brain-periphery crosstalk
Online Access:https://doi.org/10.1186/s12967-023-04044-3

Internet

https://doi.org/10.1186/s12967-023-04044-3

Similar Items