Dry and wet approaches for genome-wide functional annotation of conventional and unconventional transcriptional activators

Dry and wet approaches for genome-wide functional annotation of conventional and unconventional transcriptional activators

Transcription factors (TFs) are master gene products that regulate gene expression in response to a variety of stimuli. They interact with DNA in a sequence-specific manner using a variety of DNA-binding domain (DBD) modules. This allows to properly position their second domain, called “effector dom...

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Bibliographic Details
Main Authors: Elisabetta Levati, Sara Sartini, Simone Ottonello, Barbara Montanini
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Transcription factors
Moonlighting transcriptional activators
Transcriptional activator trap
Yeast/bacterial one-hybrid
Protein binding microarrays
HT-SELEX
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037016300228

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http://www.sciencedirect.com/science/article/pii/S2001037016300228

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