Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression

Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression

During cell division, progression through mitosis is driven by a protein phosphorylation wave. This wave namely depends on an activation-inactivation cycle of cyclin B-dependent kinase (Cdk) 1 while activities of major protein phosphatases, like PP1 and PP2A, appear directly or indirectly repressed...

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Bibliographic Details
Main Authors: Rosa Della Monica, Roberta Visconti, Nando Cervone, Angela Flavia Serpico, Domenico Grieco
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
mitosis exit
phosphatase
Fcp1
cyclin-dependent kinase
Greatwall kinase
PP2A-B55
Online Access:https://elifesciences.org/articles/10399

Internet

https://elifesciences.org/articles/10399

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