Changing shapes of glycogen-autophagy nexus in neurons: Perspective from a rare epilepsy

In brain, glycogen metabolism is predominantly restricted to astrocytes but it also indirectly supports neuronal functions. Increased accumulation of glycogen in neurons is mysteriously pathogenic triggering neurodegeneration as seen in ‘Lafora disease’ and in other transgenic animal models of neuro...

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Bibliographic Details
Main Authors: Pankaj Kumar Singh, Sweta eSingh
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2015.00014/full