C-Met as a Key Factor Responsible for Sustaining Undifferentiated Phenotype and Therapy Resistance in Renal Carcinomas

C-Met as a Key Factor Responsible for Sustaining Undifferentiated Phenotype and Therapy Resistance in Renal Carcinomas

C-Met tyrosine kinase receptor plays an important role under normal and pathological conditions. In tumor cells’ overexpression or incorrect activation of c-Met, this leads to stimulation of proliferation, survival and increase of motile activity. This receptor is also described as a marke...

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Bibliographic Details
Main Authors: Paulina Marona, Judyta Górka, Jerzy Kotlinowski, Marcin Majka, Jolanta Jura, Katarzyna Miekus
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
C-Met receptor
therapy resistance
epithelial to mesenchymal phenotype
EMT
differentiation
renal carcinoma
RCC.
Online Access:https://www.mdpi.com/2073-4409/8/3/272

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https://www.mdpi.com/2073-4409/8/3/272

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