Cargo selection in endoplasmic reticulum–to–Golgi transport and relevant diseases

Most proteins destined for the extracellular space or various intracellular compartments must traverse the intracellular secretory pathway. The first step is the recruitment and transport of cargoes from the endoplasmic reticulum (ER) lumen to the Golgi apparatus by coat protein complex II (COPII),...

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Bibliographic Details
Main Authors: Vi T. Tang, David Ginsburg
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-01-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI163838