Surfactant protein A alters endosomal trafficking of influenza A virus in macrophages

Surfactant protein A alters endosomal trafficking of influenza A virus in macrophages

Influenza A virus infection (IAV) often leads to acute lung injury that impairs breathing and can lead to death, with disproportionate mortality in children and the elderly. Surfactant Protein A (SP-A) is a calcium-dependent opsonin that binds a variety of pathogens to help control pulmonary infect...

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Bibliographic Details
Main Authors: Eric Yau, Linlin Yang, Yan Chen, Todd M. Umstead, Hannah Atkins, Zoe E. Katz, Jonathan W. Yewdell, Chintan K. Gandhi, E. Scott Halstead, Zissis C. Chroneos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
surfactant protein A
macrophages
influenza A virus
lung
collectin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.919800/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.919800/full

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