Percutaneous transhepatic cholangial drainage or antibiotic therapy worsens response to immunotherapy in advanced cholangiocarcinoma

Percutaneous transhepatic cholangial drainage or antibiotic therapy worsens response to immunotherapy in advanced cholangiocarcinoma

Abstract Background Bile duct obstruction is a common issue for patients with advanced cholangiocarcinoma (CCA). Percutaneous transhepatic cholangial drainage (PTCD) is often required to relieve the obstruction. However, PTCD may alter the intestinal microbiota, which can affect the efficacy of immu...

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Bibliographic Details
Main Authors: Qingyu Huang, Fuhao Wang, Xiang Zhang, Jing Liu, Xue Dou, Rui Feng, Kunli Zhu, Shumei Jiang, Yun Zhang, Jinbo Yue
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Cancer
Subjects:
Percutaneous transhepatic cholangial drainage
Antibiotic
Immunotherapy
Cholangiocarcinoma
Microbiota
Online Access:https://doi.org/10.1186/s12885-023-11128-2

Internet

https://doi.org/10.1186/s12885-023-11128-2

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