Percutaneous transhepatic cholangial drainage or antibiotic therapy worsens response to immunotherapy in advanced cholangiocarcinoma
Abstract Background Bile duct obstruction is a common issue for patients with advanced cholangiocarcinoma (CCA). Percutaneous transhepatic cholangial drainage (PTCD) is often required to relieve the obstruction. However, PTCD may alter the intestinal microbiota, which can affect the efficacy of immu...
Main Authors: | Qingyu Huang, Fuhao Wang, Xiang Zhang, Jing Liu, Xue Dou, Rui Feng, Kunli Zhu, Shumei Jiang, Yun Zhang, Jinbo Yue |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-023-11128-2 |
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