3D-Suspension culture platform for high throughput screening of neurotoxic chemicals using LUHMES dopaminergic neurons

3D-Suspension culture platform for high throughput screening of neurotoxic chemicals using LUHMES dopaminergic neurons

Three-dimensional (3D) cell culture in vitro promises to improve representation of neuron physiology in vivo. This inspired development of a 3D culture platform for LUHMES (Lund Human Mesencephalic) dopaminergic neurons for high-throughput screening (HTS) of chemicals for neurotoxicity. Three cultur...

Full description

Bibliographic Details
Main Authors: Zhi-Bin Tong, Ruili Huang, John Braisted, Pei-Hsuan Chu, Anton Simeonov, David L. Gerhold
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:SLAS Discovery
Subjects:
LUHMES
Parkinson's disease
Neurospheroids
3D culture
High throughput screening
Online Access:http://www.sciencedirect.com/science/article/pii/S2472555224000054

Internet

http://www.sciencedirect.com/science/article/pii/S2472555224000054

Similar Items