The Ascaris suum nicotinic receptor, ACR-16, as a drug target: Four novel negative allosteric modulators from virtual screening

Soil-transmitted helminth infections in humans and livestock cause significant debility, reduced productivity and economic losses globally. There are a limited number of effective anthelmintic drugs available for treating helminths infections, and their frequent use has led to the development of res...

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Bibliographic Details
Main Authors: Fudan Zheng, Alan P. Robertson, Melanie Abongwa, Edward W. Yu, Richard J. Martin
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320716300082