Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells

Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells

Introduction: Among numerous triterpenoids of the Cucurbitaceae family, Cucurbitacin-B (Cur-B) is being explored for its pharmacological attributes. Reports from previous studies have explicitly shown that Cur-B possesses substantial anticancer effects. The present report focuses on exploring the an...

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Bibliographic Details
Main Authors: Ahmed Alafnan, Nasrin E. Khalifa, Talib Hussain, Mhdia Elhadi Osman
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Pharmacology
Subjects:
anti-cancer
apoptosis
cell cycle
cucurbitacin-B
Notch signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1206981/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1206981/full

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