Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells
Introduction: Among numerous triterpenoids of the Cucurbitaceae family, Cucurbitacin-B (Cur-B) is being explored for its pharmacological attributes. Reports from previous studies have explicitly shown that Cur-B possesses substantial anticancer effects. The present report focuses on exploring the an...
Main Authors: | Ahmed Alafnan, Nasrin E. Khalifa, Talib Hussain, Mhdia Elhadi Osman |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-06-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1206981/full |
Similar Items
-
Corrigendum: Cucurbitacin-B instigates intrinsic apoptosis and modulates Notch signaling in androgen-dependent prostate cancer LNCaP cells
by: Ahmed Alafnan, et al.
Published: (2023-09-01) -
Cucurbitacin-B Exerts Anticancer Effects through Instigation of Apoptosis and Cell Cycle Arrest within Human Prostate Cancer PC3 Cells via Downregulating JAK/STAT Signaling Cascade
by: Ahmed Alafnan, et al.
Published: (2022-10-01) -
Cucurbitacins: elucidation of their interactions with the cytoskeleton
by: Xiaojuan Wang, et al.
Published: (2017-05-01) -
Pharmacokinetics and Biological Activity of Cucurbitacins
by: Eugenia Elisa Delgado-Tiburcio, et al.
Published: (2022-10-01) -
Influence of cucurbitacin-containing phytonematicides on selected nutrient elements in leaf tissues of green bean under greenhouse conditions
by: P. W. Mashela, et al.
Published: (2017-11-01)