Chimeric proton-pumping rhodopsins containing the cytoplasmic loop of bovine rhodopsin.

Chimeric proton-pumping rhodopsins containing the cytoplasmic loop of bovine rhodopsin.

G-protein-coupled receptors (GPCRs) transmit stimuli to intracellular signaling systems. Rhodopsin (Rh), which is a prototypical GPCR, possesses an 11-cis retinal. Photoisomerization of 11-cis to all-trans leads to structural changes in the protein of cytoplasmic loops, activating G-protein. Microbi...

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Bibliographic Details
Main Authors: Kengo Sasaki, Takahiro Yamashita, Kazuho Yoshida, Keiichi Inoue, Yoshinori Shichida, Hideki Kandori
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3951393?pdf=render

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http://europepmc.org/articles/PMC3951393?pdf=render

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