Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice

Aberrant expression of FBXO22 is associated with propofol-induced synaptic plasticity and cognitive dysfunction in adult mice

Recent observation demonstrated that prolonged anesthesia modifies brain synaptic architecture in all ages, including adult. Propofol is the most commonly utilized anesthetics at clinic. Whether repeated administration of propofol modulates cognitive impairment in adults and changes synaptic plastic...

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Bibliographic Details
Main Authors: Xiaoxuan Yang, Chen Chen, Dongmei Qu, Yanping Liu, Ning Wang, Haibi Wang, Youjia Fan, Yushan Zhou, Buwei Yu, Qingsheng Xue, Yuqing Wu, Han Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
propofol
FBXO22
hippocampus
general anesthesia
neurocognition
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1028148/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.1028148/full

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