Selective Export into Extracellular Vesicles and Function of tRNA Fragments during T Cell Activation

Summary: The discovery of microRNA (miRNA) sorting into extracellular vesicles (EVs) revealed a novel mode of intercellular communication and uncovered a link between cellular endomembrane compartments and small RNAs in EV-secreting cells. Using a two-step ultracentrifugation procedure to isolate EV...

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Bibliographic Details
Main Authors: Ni-Ting Chiou, Robin Kageyama, K. Mark Ansel
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718318497