Fluorescence intensity and lifetime imaging of lipofuscin-like autofluorescence for label-free predicting clinical drug response in cancer

Fluorescence intensity and lifetime imaging of lipofuscin-like autofluorescence for label-free predicting clinical drug response in cancer

Conventional techniques for in vitro cancer drug screening require labor-intensive formalin fixation, paraffin embedding, and dye staining of tumor tissues at fixed endpoints. This way of assessment discards the valuable pharmacodynamic information in live cells over time. Here, we found endogenous...

Full description

Bibliographic Details
Main Authors: Yinghan Yan, Fuqiang Xing, Jiayue Cao, Yiling Hu, Ling Li, Zhengyin Gao, Hao Jia, Kai Miao, Fangyuan Shao, Chu-Xia Deng, Kathy Qian Luo, Leo Tsz on Lee, Tzu-Ming Liu
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Redox Biology
Subjects:
Apoptosis
Autofluorescence
Label-free
Lipofuscin
Necrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722003500

Internet

http://www.sciencedirect.com/science/article/pii/S2213231722003500

Similar Items