A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery

A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery

Iatrogenic injury of the ureters is a feared complication of laparoscopic abdominal surgery. Here the authors present the NIR fluorophore ZW800-1 as an intraoperative imaging agent for ureter mapping, showing its safety, pharmacokinetic properties, and efficacy in healthy volunteers and patients und...

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Bibliographic Details
Main Authors: Kim S. de Valk, Henricus J. Handgraaf, Marion M. Deken, Babs G. Sibinga Mulder, Adrianus R. Valentijn, Anton G. Terwisscha van Scheltinga, Joeri Kuil, Michiel J. van Esdonk, Jaap Vuijk, Rob F. Bevers, Koen C. Peeters, Fabian A. Holman, John V. Frangioni, Jacobus Burggraaf, Alexander L. Vahrmeijer
Format: Article
Language:English
Published: Nature Portfolio 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11014-1

Internet

https://doi.org/10.1038/s41467-019-11014-1

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