Combinatorial therapeutic drug delivery of riboflavin and dexamethasone for the treatment of keratoconus affected corneas of mice: Ex vivo permeation and hemolytic toxicity

Abstract The aim of this study was to formulate the thermoreversible gel containing riboflavin and dexamethasone to treat keratoconus. Gel was prepared by the cold method by mixing the poloxamer 407 as a thermosensitive polymer and HPMC as viscosity enhancing agent. The formulation was evaluated for...

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Bibliographic Details
Main Authors: Na Wo, Jiabin Zhai
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Micro & Nano Letters
Online Access:https://doi.org/10.1049/mna2.12079