Circulating Levels of Anti-C1q and Anti-Factor H Autoantibodies and Their Targets in Normal Pregnancy and Preeclampsia

Circulating Levels of Anti-C1q and Anti-Factor H Autoantibodies and Their Targets in Normal Pregnancy and Preeclampsia

Preeclampsia (PE) generally manifests in the second half of pregnancy with hypertension and proteinuria. The understanding of the origin and mechanism behind PE is incomplete, although there is clearly an immune component to this disorder. The placenta constitutes a complicated immune interface betw...

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Bibliographic Details
Main Authors: Douwe Jan Dijkstra, A. Inkeri Lokki, Lobke Marijn Gierman, Nicole Veronique Borggreven, Carin van der Keur, Michael Eikmans, Kyra Andrea Gelderman, Hannele Laivuori, The FINNPEC Core Investigator Group, Ann-Charlotte Iversen, Marie-Louise P. van der Hoorn, Leendert Adrianus Trouw, Seppo Heinonen, Eero Kajantie, Juha Kere, Katja Kivinen, Anneli Pouta
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
C1q
complement
factor H
autoantibodies
preeclampsia
pregnancy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.842451/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.842451/full

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