Immunostimulating RNA Delivered by P1500 PEGylated Cationic Liposomes Limits Influenza Infection in C57Bl/6 Mice

Immunostimulating RNA Delivered by P1500 PEGylated Cationic Liposomes Limits Influenza Infection in C57Bl/6 Mice

The emergence of highly pathogenic viruses and a high speed of infection spread put forward the problem of the development of novel antivirals and their delivery vehicles. In this study, we investigated the antiviral effect of the previously identified immunostimulatory 19-bp dsRNA (isRNA) with 3′-n...

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Bibliographic Details
Main Authors: Elena P. Goncharova, Aleksandra V. Sen‘kova, Innokenty A. Savin, Tat‘yana O. Kabilova, Marina A. Zenkova, Valentin V. Vlassov, Elena L. Chernolovskaya
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceutics
Subjects:
immunostimulating RNA
influenza a virus
PEGylated cationic liposomes
IFN-α
innate immunity
Online Access:https://www.mdpi.com/1999-4923/12/9/875

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https://www.mdpi.com/1999-4923/12/9/875

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