Evaluation of <it>NTHL1</it>, <it>NEIL1</it>, <it>NEIL2</it>, <it>MPG</it>, <it>TDG</it>, <it>UNG </it>and <it>SMUG1 </it>genes in familial colorectal cancer predisposition

<p>Abstract</p> <p>Background</p> <p>The observation that germline mutations in the oxidative DNA damage repair gene <it>MUTYH </it>cause colorectal cancer (CRC) provides strong evidence that dysregulation of the base excision repair (BER) pathway influences...

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Bibliographic Details
Main Authors: Chandler Ian, Lubbe Steven, Vijayakrishnan Jairam, Bagratuni Tina, Broderick Peter, Houlston Richard S
Format: Article
Language:English
Published: BMC 2006-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/243