Molecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia 2
Multiple endocrine neoplasia type 2 is an inherited cancer syndrome characterized by tumors of thyroid and adrenal tissues. Germline mutations of the REarranged during Transfection (RET) proto-oncogene, leading to its unregulated activation, are the underlying cause of this disease. Multiple endocri...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier España
2012-01-01
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Series: | Clinics |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322012001300014 |