Translation dysregulation in neurodegenerative diseases: a focus on ALS

Abstract RNA translation is tightly controlled in eukaryotic cells to regulate gene expression and maintain proteome homeostasis. RNA binding proteins, translation factors, and cell signaling pathways all modulate the translation process. Defective translation is involved in multiple neurological di...

Full description

Bibliographic Details
Main Authors: Shaopeng Wang, Shuying Sun
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s13024-023-00642-3