Peripheral interleukin-6-associated microglial QUIN elevation in basolateral amygdala contributed to cognitive dysfunction in a mouse model of postoperative delirium
BackgroundDeveloping effective approaches for postoperative delirium has been hampered due to the lack of a pathophysiologically similar animal model to offer insights into the pathogenesis. The study, therefore, aimed to develop a delirium-like mouse model and explore the underlying mechanism.Metho...
Main Authors: | Jing-Lan Mu, Xiao-Dong Liu, Ye-Hong Dong, Ying-Ying Fang, Shi-Da Qiu, Fu Zhang, Ke-Xuan Liu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.998397/full |
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