Integrated multiomics analysis and machine learning refine molecular subtypes and prognosis for muscle-invasive urothelial cancer

Integrated multiomics analysis and machine learning refine molecular subtypes and prognosis for muscle-invasive urothelial cancer

Muscle-invasive urothelial cancer (MUC), characterized by high aggressiveness and significant heterogeneity, is currently lacking highly precise individualized treatment options. We used a computational pipeline to synthesize multiomics data from MUC patients using 10 clustering algorithms, which we...

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Bibliographic Details
Main Authors: Guangdi Chu, Xiaoyu Ji, Yonghua Wang, Haitao Niu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Bioinformatics
muscle-invasive urothelial cancer
multiomics
machine learning
immunotherapy
prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123001440

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http://www.sciencedirect.com/science/article/pii/S2162253123001440

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