Heterogeneous Tau Oligomers as Molecular Targets for Alzheimer’s Disease and Related Tauopathies

Tauopathies, including Alzheimer’s disease (AD), are a group of neurodegenerative disorders characterized by pathological aggregation of microtubule binding protein tau. The presence of tau neurofibrillary tangles, which are insoluble β-sheet fibrils, in the brain has been the histopathological hall...

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Bibliographic Details
Main Author: Chih Hung Lo
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biophysica
Subjects:
Online Access:https://www.mdpi.com/2673-4125/2/4/39