Large-scale screen for modifiers of ataxin-3-derived polyglutamine-induced toxicity in Drosophila.

Large-scale screen for modifiers of ataxin-3-derived polyglutamine-induced toxicity in Drosophila.

Polyglutamine (polyQ) diseases represent a neuropathologically heterogeneous group of disorders. The common theme of these disorders is an elongated polyQ tract in otherwise unrelated proteins. So far, only symptomatic treatment can be applied to patients suffering from polyQ diseases. Despite exten...

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Main Authors: Hannes VoSSfeldt, Malte Butzlaff, Katja PrüSSing, Róisín-Ana Ní Chárthaigh, Peter Karsten, Anne Lankes, Sabine Hamm, Mikael Simons, Boris Adryan, Jörg B Schulz, Aaron Voigt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3489908?pdf=render

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http://europepmc.org/articles/PMC3489908?pdf=render

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