Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors

Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors

After entry into the target cell, the human immunodeficiency virus type I (HIV) integrates into the host genome and becomes a proviral eukaryotic transcriptional unit. Transcriptional regulation of provirus gene expression is critical for HIV replication. Basal transcription from the integrated HIV...

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Bibliographic Details
Main Authors: Susana Valente, Guillaume Mousseau
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Biology
Subjects:
Tat
TAR
inhibitors
small molecule compounds
transcription
latency
chronic cells
HIV-1
HIV-2
Online Access:http://www.mdpi.com/2079-7737/1/3/668

Internet

http://www.mdpi.com/2079-7737/1/3/668

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