Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy.

Developing patient derived models from individual tumors that capture the biological heterogeneity and mutation landscape in advanced prostate cancer is challenging, but essential for understanding tumor progression and delivery of personalized therapy in metastatic castrate resistant prostate cance...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Manish Kohli, Liguo Wang, Fang Xie, Hugues Sicotte, Ping Yin, Scott M Dehm, Steven N Hart, Peter T Vedell, Poulami Barman, Rui Qin, Douglas W Mahoney, Rachel E Carlson, Jeanette E Eckel-Passow, Thomas D Atwell, Patrick W Eiken, Brendan P McMenomy, Eric D Wieben, Gautam Jha, Rafael E Jimenez, Richard Weinshilboum, Liewei Wang
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2015-01-01
Sraith:PLoS ONE
Rochtain ar líne:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0145176&type=printable