Identification of new head and neck squamous cell carcinoma subtypes and development of a novel score system (PGSscore) based on variations in pathway activity between tumor and adjacent non-tumor samples

Identification of new head and neck squamous cell carcinoma subtypes and development of a novel score system (PGSscore) based on variations in pathway activity between tumor and adjacent non-tumor samples

The influence of adjacent non-tumor tissue characteristics on patient outcomes in head and neck squamous cell carcinoma (HNSC) remains unclear. In HNSC, subtype identification is generally tumor-based, and most prognosis-related studies focus on a single gene set. Here, we performed Gene Set Variati...

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Bibliographic Details
Main Authors: Yufan Zhang, Ying Liu, Junfei Huang, Zhiqi Hu, Yong Miao
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Head and neck squamous cell carcinoma
Subtype
Gene set
PGSscore
Immunotherapy
Prognosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022003919

Internet

http://www.sciencedirect.com/science/article/pii/S2001037022003919

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