Antioxidant Response in Human X-Linked Adrenoleukodystrophy Fibroblasts

Antioxidant Response in Human X-Linked Adrenoleukodystrophy Fibroblasts

Redox imbalance, mitochondrial dysfunction, and inflammation play a major role in the pathophysiology of X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease caused by mutations in the ABCD1 gene, encoding the protein responsible for peroxisomal import and degradation of ver...

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Bibliographic Details
Main Authors: Sara Petrillo, Jessica D’Amico, Francesco Nicita, Caterina Torda, Gessica Vasco, Enrico S. Bertini, Marco Cappa, Fiorella Piemonte
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antioxidants
Subjects:
X-ALD
AMN
cALD
lipid peroxidation
glutathione peroxidase 4
NAD(P)H coenzyme Q oxidoreductase 1
Online Access:https://www.mdpi.com/2076-3921/11/11/2125

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https://www.mdpi.com/2076-3921/11/11/2125

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