Exploring the Role of Mutations in Fanconi Anemia Genes in Hereditary Cancer Patients

Exploring the Role of Mutations in Fanconi Anemia Genes in Hereditary Cancer Patients

Fanconi anemia (FA) is caused by biallelic mutations in FA genes. Monoallelic mutations in five of these genes (<i>BRCA1, BRCA2, PALB2, BRIP1</i> and <i>RAD51C</i>) increase the susceptibility to breast/ovarian cancer and are used in clinical diagnostics as bona-fide heredita...

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Bibliographic Details
Main Authors: Jesús del Valle, Paula Rofes, José Marcos Moreno-Cabrera, Adriana López-Dóriga, Sami Belhadj, Gardenia Vargas-Parra, Àlex Teulé, Raquel Cuesta, Xavier Muñoz, Olga Campos, Mónica Salinas, Rafael de Cid, Joan Brunet, Sara González, Gabriel Capellá, Marta Pineda, Lídia Feliubadaló, Conxi Lázaro
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
Breast cancer risk
Breast and ovarian cancer risk
Fanconi Anemia
Hereditary Cancer
NGS panel sequencing
Online Access:https://www.mdpi.com/2072-6694/12/4/829

Internet

https://www.mdpi.com/2072-6694/12/4/829

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