Oxidation of the Platinum(II) Anticancer Agent [Pt{(<i>p</i>-BrC<sub>6</sub>F<sub>4</sub>)NCH<sub>2</sub>CH<sub>2</sub>NEt<sub>2</sub>}Cl(py)] to Platinum(IV) Complexes by Hydrogen Peroxide

Pt<sup>IV</sup> coordination complexes are of interest as prodrugs of Pt<sup>II</sup> anticancer agents, as they can avoid deactivation pathways owing to their inert nature. Here, we report the oxidation of the antitumor agent [Pt<sup>II</sup>(<i>p</i>...

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Bibliographic Details
Main Authors: Ruchika Ojha, Peter C. Junk, Alan M. Bond, Glen B. Deacon
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/28/17/6402