Development of multivalent nanobodies blocking SARS-CoV-2 infection by targeting RBD of spike protein

Development of multivalent nanobodies blocking SARS-CoV-2 infection by targeting RBD of spike protein

Abstract Background The outbreak and pandemic of coronavirus SARS-CoV-2 caused significant threaten to global public health and economic consequences. It is extremely urgent that global people must take actions to develop safe and effective preventions and therapeutics. Nanobodies, which are derived...

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Bibliographic Details
Main Authors: Qizhong Lu, Zongliang Zhang, Hexian Li, Kunhong Zhong, Qin Zhao, Zeng Wang, Zhiguo Wu, Donghui Yang, Shuang Sun, Nian Yang, Meijun Zheng, Qiang Chen, Cheng Long, Wenhao Guo, Hui Yang, Chunlai Nie, Aiping Tong
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Nanobiotechnology
Subjects:
SARS-CoV-2
Nanobody
Spike
RBD
Pseudovirus neutralization
Online Access:https://doi.org/10.1186/s12951-021-00768-w

Internet

https://doi.org/10.1186/s12951-021-00768-w

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