Chronic exposure to cigarette smoke extract increases nicotine withdrawal symptoms in adult and adolescent male rats
The aim of the current study was to determine whether non-nicotine constituents of cigarette smoke contribute to nicotine dependence in adolescent and adult male Sprague Dawley rats. For 10 days animals were given three times daily intravenous injections of nicotine (1.5 mg/kg/day) or cigarette smok...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-09-01
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| Series: | Advances in Drug and Alcohol Research |
| Subjects: | |
| Online Access: | https://www.frontierspartnerships.org/articles/10.3389/adar.2023.11324/full |