Construction and Evaluation of the Immunogenicity and Protective Efficacy of Recombinant Replication-Deficient Human Adenovirus-5 Expressing Genotype VII Newcastle Disease Virus F Protein and Infectious Bursal Disease Virus VP2 Protein

Construction and Evaluation of the Immunogenicity and Protective Efficacy of Recombinant Replication-Deficient Human Adenovirus-5 Expressing Genotype VII Newcastle Disease Virus F Protein and Infectious Bursal Disease Virus VP2 Protein

Newcastle disease (ND) and infectious bursal disease (IBD) are two key infectious diseases that significantly threaten the health of the poultry industry. Although existing vaccinations can effectively prevent and treat these two diseases through multiple immunizations, frequent immunization stresse...

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Bibliographic Details
Main Authors: Ting Xu, Ting Xiong, Wenting Xie, Jing Wu, Xiao Liu, Guimin Li, Yadi Lv, Linyu Li, Zekun Yang, Han Wang, Dingxiang Liu, Ruiai Chen
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Vaccines
Subjects:
NDV F protein
IBDV VP2 protein
rHAdV-5-based vaccine candidates
humoral immune response
cellular immune response
Online Access:https://www.mdpi.com/2076-393X/11/6/1051

Internet

https://www.mdpi.com/2076-393X/11/6/1051

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