MmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growth.

MmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growth.

Lipid metabolism plays an important role during the lifetime of Mycobacterium tuberculosis, the causative agent of tuberculosis. Although M. tuberculosis possesses numerous lipolytic enzymes, very few have been characterized yet at a biochemical/pharmacological level. This study was devoted to the M...

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Bibliographic Details
Main Authors: Vincent Delorme, Sadia V Diomandé, Luc Dedieu, Jean-François Cavalier, Frédéric Carrière, Laurent Kremer, Julien Leclaire, Frédéric Fotiadu, Stéphane Canaan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460867?pdf=render

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http://europepmc.org/articles/PMC3460867?pdf=render

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